DICE

A Unifying Modeling Approach Expressly Designed to Meet the Needs of Health Economic Analysis

  • Publications

    Publication

    Discretely Integrated Condition Event (DICE) Simulation for Pharmacoeconomics. Pharmacoeconomics. 2016 Jul;34(7):665-72. doi: 10.1007/s40273-016-0394-z. ABSTRACT
  • White Papers

    Whitepaper

    Rolling the DICE: Discretely Integrated Condition Event Simulation for Health Economic Analyses

    Authors: J. Jaime Caro MDCM, FRCPC, FACP, Chief Scientist, Evidera

    Year: 2016

    View
  • Presentations

    Poster

    PRM84: Structural Sensitivity Analyses of Mortality and Location of Care in a Simulation of Alzheimer's Disease

    ISPOR 21st Annual International Meeting – 2016:

    Washington, DC, USA
    21-May-2016

    Authors/Presenters: Kansal A, Dos Santos R, Tafazzoli A

    Year: 2016

    View

    Poster

    PRM80: Improving Precision by Applying Disease Progression Equations from Multiple Sources in the Alzheimer's Disease Archimedes Condition Event (ACE) Simulator

    ISPOR 21st Annual International Meeting – 2016:

    Washington, DC, USA
    21-May-2016

    Authors/Presenters: Tafazzoli A, Dos Santos R, Ishak J, Krotneva M, Kansal A

    Year: 2016

    View

    Oral Presentation

    DICE Simulation for HTA: A New, Unifying Method

    CADTH Symposium – 2016:

    Ottawa, ON, Canada
    10-Apr-2016

    Authors/Presenters: Caro JJ

    Year: 2016

    See More
  • Fact Sheets

    Fact Sheet

    DICE: Discretely Integrated Condition Event simulation
    Download

Several decision-analytic modeling techniques are used today for informing health technology assessments (HTAs). These methods have been borrowed from other fields, in the absence of any health economic-specific tools, and consequently their application in our field often leads to oversimplification of the problem and/or loss of transparency. Discretely Integrated Condition Event (DICE) simulation is a novel and unifying approach specifically designed to meet HE modeling needs for accurate representation of HTA problems in a transparent and flexible way. Experience with DICE is growing rapidly as many companies are adopting it for their disease models, with applications spanning early decision analysis through formal health economic submissions.

EviDICE conditions events3

The core components of DICE are events and conditions, which are integrated at discrete time points. This simple structure can be used to reflect any aspect of a disease and its management, including valuation (e.g., QALYs, costs) of key outcomes of interest. Therefore, its applications range from basic cost‐consequence and budget impact analyses to complex cost‐effectiveness and full disease simulations.

Evidera has developed EviDICE®, a user-friendly, transparent and validated Microsoft Excel-based platform for DICE applications. EviDICE provides an efficient and effective way to implement DICE using a wealth of built-in tools.

Learn more about DICE here:
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Read more about how DICE works in a recent publication by the originator of DICE here:
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Download a demo to experience DICE:

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Learn more about an application of DICE, the AD ACE:
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  • Publications

    Publication

    Discretely Integrated Condition Event (DICE) Simulation for Pharmacoeconomics. Pharmacoeconomics. 2016 Jul;34(7):665-72. doi: 10.1007/s40273-016-0394-z. ABSTRACT
  • White Papers

    Whitepaper

    Rolling the DICE: Discretely Integrated Condition Event Simulation for Health Economic Analyses

    Authors: J. Jaime Caro MDCM, FRCPC, FACP, Chief Scientist, Evidera

    Year: 2016

    View
  • Presentations

    Poster

    PRM84: Structural Sensitivity Analyses of Mortality and Location of Care in a Simulation of Alzheimer's Disease

    ISPOR 21st Annual International Meeting – 2016:

    Washington, DC, USA
    21-May-2016

    Authors/Presenters: Kansal A, Dos Santos R, Tafazzoli A

    Year: 2016

    View

    Poster

    PRM80: Improving Precision by Applying Disease Progression Equations from Multiple Sources in the Alzheimer's Disease Archimedes Condition Event (ACE) Simulator

    ISPOR 21st Annual International Meeting – 2016:

    Washington, DC, USA
    21-May-2016

    Authors/Presenters: Tafazzoli A, Dos Santos R, Ishak J, Krotneva M, Kansal A

    Year: 2016

    View

    Oral Presentation

    DICE Simulation for HTA: A New, Unifying Method

    CADTH Symposium – 2016:

    Ottawa, ON, Canada
    10-Apr-2016

    Authors/Presenters: Caro JJ

    Year: 2016

    See More
  • Fact Sheets

    Fact Sheet

    DICE: Discretely Integrated Condition Event simulation
    Download
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