Bryan has focused his career on developing and improving methods, policies and applications for evidence-based healthcare. As a senior advisor he provides thought leadership and strategic guidance to Evidera’s global clients and other industry collaborators, as well as to his Evidera colleagues.
In his previous role as Chief Science Officer of the Patient-Centered Research Institute, Bryan was responsible for leading the development and implementation of PCORI’s patient-centered comparative clinical effectiveness research agenda. Bryan previously founded the outcomes research firm MEDTAP® International, serving as its Chairman, President, and Chief Executive Officer, and was the Senior Vice President for Science Policy at the United BioSource Corporation. Earlier, Bryan was Director of Battelle’s Centers for Public Health Research and Evaluation; Director of the Office of Research and Demonstrations, Centers for Medicare and Medicaid Services; and a Senior Analyst at the Office of Technology Assessment of the United States Congress. Bryan’s research has focused on improving methods and related policies for more efficient healthcare decision making. He has authored more than 100 scientific publications, including three textbooks on health technology assessment, health policy, and health economics.
In 2008, Bryan founded the Pragmatic Approaches to Comparative Effectiveness (PACE) Initiative, which studied novel methods to conduct analytical efficiency comparative effectiveness trials. Previously, he founded the Bayesian Initiative in Health Economics and Outcomes Research and presently chairs the Scientific Collaboration of EXCITE International, whose mission is to pioneer an international platform for coordinated market approval and market access of medical devices. He has been an advisor to numerous government and nonprofit agencies, as well as pharmaceutical and device firms worldwide; a member or chair of socioeconomic and public health policy advisory boards for leading biopharmaceutical companies; a member of the Medicare Evidence Development & Coverage Advisory Committee (MedCAC), and a member of the Board of Directors for the Medical Device Innovation Consortium (MDIC). Bryan is also a past president of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and in 2008 received the Society’s Avedis Donabedian Outcomes Research Lifetime Achievement Award. He has held adjunct faculty positions in the Department of Health Policy at Jefferson Medical College, the Leonard D. Schaeffer Center for Health Policy and Economics at the University of Southern California, and the Department of Health Services, George Washington University.
A former Special Forces Officer, Bryan is a Lieutenant Colonel (Retired), U.S. Army Reserves. He holds MS (public health) and MBA degrees from the University of Massachusetts at Amherst, and a PhD in health services research from the University of California at Los Angeles.