Following Grammati’s work as a dental officer in the UK, she also has over 10 years’ experience as a university teacher, clinical and epidemiological researcher, systematic reviewer and statistical advisor in academic, advisory body and health policy settings. Grammati spent over six years as a senior research fellow involved in producing evidence synthesis (quantitative and qualitative reviews and complex meta-analyses including network meta-analyses [NMAs]) to inform the National Institute for Health and Care Excellence (NICE) guidelines in a wide range of health conditions, such as epilepsy, lipid modification, stroke rehabilitation, chronic hepatitis B, pneumonia, physical health of prisoners, diabetes in pregnancy, and intrapartum care for high-risk women. Latterly, Grammati became a NICE Clinical Guideline Lead and, thus, had overall scientific and operational responsibility for guideline development from scoping to publication, including provision of expert opinion and quality assuring methodological aspects across different guideline topics. The role included being the lead author of two NICE guidelines: Menopause: diagnosis and management (published November 2015); and Preterm labour and birth (published November 2015).
Grammati’s methodological expertise is based on epidemiological and statistical knowledge and experience gained through formal academic qualifications and professional participation in working methodological groups (e.g., GRADE working group on NMAs, NICE methodological NMA subgroup and Data Extraction for Complex Meta-Analyses (DECIMAL) project). Her publication portfolio spans various clinical and methodological areas such as articles reporting systematic reviews conducted to inform NICE guidelines, official summaries of NICE guidelines published in the BMJ, and presentations of statistical analyses from multiple epidemiological and clinical studies. Grammati has also been invited to provide expertise on decision-making at several international meetings. She was, for example, the expert advisor to the World Health Organization in the use of NMA in developing its Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection.
Grammati qualified as a clinical dentist at the University of Athens (Greece) and has an MSc in Dental Public Health (from the Institute of Dentistry, Barts and The London School of Medicine and Dentistry) and a PhD in Oral Epidemiology from the University of London.