Shien has designed and conducted numerous evaluations of health technologies (e.g., cost-effectiveness, cost-benefit and budget impact analyses), retrospective database analyses and analyses of patient-reported outcomes data from clinical trials. Highly experienced with advanced modeling techniques such as discrete event simulation and Markov modeling, he has modeled the course of diseases in many areas, particularly in Alzheimer’s disease, multiple myeloma, multiple sclerosis and schizophrenia.
Skilled in the application of various statistical and simulation packages, including ARENA, Excel, SPSS and TreeAge, Shien has published many scientific papers in numerous peer-reviewed journals, such as Current Medical Research and Opinion, PharmacoEconomics, International Journal of Technology Assessment in Health Care and Ostomy and Wound Management, and he has presented at various conferences including the World Congress of Cardiology, International Society of Pharmacoeconomics and Outcomes Research, Academy of Managed Care Pharmacy and American Heart Association. He is also a reviewer for various peer-reviewed journals, such as Value in Health and European Journal of Health Economics.
Shien completed his doctorate in public health with a concentration in health policy and management from Saint Louis University in St. Louis. He also received professional training in cost-effectiveness analysis at the School of Public Health, Harvard University.