The Migraine Physical Function Impact Diary (MPFID) is a 13-item self-report questionnaire, developed to measure the subjective impact of migraine on physical functioning (everyday activities and physical impairment) in the past 24 hours. It is intended for use in adults (age 18 or older) with episodic migraine (EM) or chronic migraine (CM), with or without aura. The diary was developed using methods consistent with the regulatory guidance on patient-reported outcome (PRO) measures to support label claims about the benefit of treatments1.

The MPFID was designed to be completed every day to capture the day-to-day variability of the impact of migraine, on migraine and non-migraine days.

The MPFID was conceptually designed to capture both ‘acts’ and ‘tasks’ associated with the impact of migraine on functioning2. The MPFID includes multiple domains to assess the impact of migraine on physical functioning:

  • Impact on Everyday Activities (EA)
  • Physical Impairment (PI)
  • Overall Impact on Everyday Activities

1Food and Drug Administration. Guidance for industry on patient-reported outcome measures: use in medical product development to support labeling claims. Fed Reg.  2009;74:65132-65133.
2World Health Organization. International Classification of Functioning, Disability and Health. ICF. Geneva: World Health Organization. 2001.